{"id":7027,"date":"2026-02-06T10:03:01","date_gmt":"2026-02-06T09:03:01","guid":{"rendered":"https:\/\/nehomy.com\/?page_id=7027"},"modified":"2026-04-27T10:43:46","modified_gmt":"2026-04-27T08:43:46","slug":"les-causes-de-lirc","status":"publish","type":"page","link":"https:\/\/nehomy.com\/en\/what-is-ckd\/the-causes-of-ckd\/","title":{"rendered":"What are the causes?"},"content":{"rendered":"<div data-elementor-type=\"wp-page\" data-elementor-id=\"7027\" class=\"elementor elementor-7027\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-76b3b301 e-flex e-con-boxed e-con e-parent\" data-id=\"76b3b301\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-aa1bb55 e-con-full e-flex e-con e-child\" data-id=\"aa1bb55\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-3e09771d elementor-widget elementor-widget-text-editor\" data-id=\"3e09771d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h1 class=\"translation-block\">What are<br>the causes?<sup>22,23<\/sup><\/h1>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-d113ed5 e-con-full e-flex e-con e-child\" data-id=\"d113ed5\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-1873af0 elementor-widget elementor-widget-image\" data-id=\"1873af0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"1\" height=\"1\" src=\"https:\/\/nehomy.com\/wp-content\/uploads\/2026\/02\/image-symptome.svg\" class=\"attachment-large size-large wp-image-7017\" alt=\"\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-019873f e-flex e-con-boxed e-con e-parent\" data-id=\"019873f\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-f837d58 elementor-widget elementor-widget-text-editor\" data-id=\"f837d58\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p style=\"text-align: center;\">Chronic kidney disease (CKD) can be caused by several factors, often acting together. These causes may be medical, genetic or linked to exposure to toxic substances.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-ecf9ac5 e-flex e-con-boxed e-con e-parent\" data-id=\"ecf9ac5\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-e4cb9c7 e-con-full e-flex e-con e-child\" data-id=\"e4cb9c7\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t<div class=\"elementor-element elementor-element-219be38 e-con-full e-flex e-con e-child\" data-id=\"219be38\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-9b2810b elementor-widget elementor-widget-image\" data-id=\"9b2810b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"1\" height=\"1\" src=\"https:\/\/nehomy.com\/wp-content\/uploads\/2026\/02\/bonhomme.svg\" class=\"attachment-large size-large wp-image-7021\" alt=\"\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-38df7d7 e-con-full e-flex e-con e-child\" data-id=\"38df7d7\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-7b503e3 elementor-widget elementor-widget-text-editor\" data-id=\"7b503e3\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h2 class=\"translation-block\">Underlying medical conditions<\/h2><p>Certain chronic diseases directly affect the kidneys and lead to their gradual deterioration:<\/p><ul><li class=\"translation-block\"><strong>Diabetes (Type 1 and Type 2)<\/strong> : this is the <strong>leading cause of CKD<\/strong> worldwide. Poorly controlled blood sugar levels damage the small blood vessels in the kidneys (diabetic nephropathy), progressively reducing their filtering capacity.<\/li><li class=\"translation-block\"><strong>High blood pressure<\/strong> : High blood pressure places excessive strain on the blood vessels of the kidneys, causing them to harden and narrow, which reduces their efficiency. Without proper control, this can accelerate the loss of kidney function.<\/li><li class=\"translation-block\"><strong>Autoimmune diseases:<\/strong> Certain diseases, such as <strong>systemic lupus erythematosus<\/strong> or <strong>vasculitis<\/strong>, attack the kidneys and cause chronic inflammation of kidney structures (glomeruli and tubules), which can lead to progressive kidney failure.<\/li><li><strong>Chronic pyelonephritis<\/strong> : this bacterial kidney infection can cause persistent inflammation and irreversible damage to kidney tissue, especially when infections recur.<\/li><li><strong>Glomerulonephritis<\/strong> : this refers to inflammation of the kidney filters (glomeruli), caused by infections, autoimmune diseases or immune disorders. If left untreated, it can lead to a gradual decline in kidney function.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-918f0f3 e-flex e-con-boxed e-con e-parent\" data-id=\"918f0f3\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-51c53fc e-con-full e-flex e-con e-child\" data-id=\"51c53fc\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t<div class=\"elementor-element elementor-element-9195d25 e-con-full e-flex e-con e-child\" data-id=\"9195d25\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-1bea496 elementor-widget elementor-widget-text-editor\" data-id=\"1bea496\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h2 class=\"translation-block\"><strong>Genetic and hereditary<\/strong> factors<\/h2><p>Some inherited diseases directly affect the kidneys and may lead to kidney failure over time:<\/p><ul><li class=\"translation-block\"><strong>Autosomal dominant polycystic kidney disease (ADPKD)<\/strong>: this genetic disorder causes <strong>fluid-filled cysts<\/strong> to develop in the kidneys, leading to enlargement of the kidneys and reduced filtering capacity. It is one of the main genetic causes of CKD.<\/li><li class=\"translation-block\"><strong>Alport syndrome<\/strong> : this inherited condition affects the membranes of the glomeruli, causing progressive kidney damage, often associated with hearing loss and eye disorders.<\/li><li class=\"translation-block\"><strong>Other hereditary forms of glomerulonephritis<\/strong> may also contribute to the long-term development of chronic kidney disease.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-841ee78 e-con-full e-flex e-con e-child\" data-id=\"841ee78\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c0bac2e elementor-widget elementor-widget-image\" data-id=\"c0bac2e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"1\" height=\"1\" src=\"https:\/\/nehomy.com\/wp-content\/uploads\/2026\/02\/bonhomme-2.svg\" class=\"attachment-large size-large wp-image-7022\" alt=\"\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-2453ccf e-flex e-con-boxed e-con e-parent\" data-id=\"2453ccf\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-07949fa e-con-full e-flex e-con e-child\" data-id=\"07949fa\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t<div class=\"elementor-element elementor-element-19414d7 e-con-full e-flex e-con e-child\" data-id=\"19414d7\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-2d0f5bd elementor-widget elementor-widget-image\" data-id=\"2d0f5bd\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"1\" height=\"1\" src=\"https:\/\/nehomy.com\/wp-content\/uploads\/2026\/02\/madame.svg\" class=\"attachment-large size-large wp-image-7023\" alt=\"\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-3ba66e2 e-con-full e-flex e-con e-child\" data-id=\"3ba66e2\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-9d1e151 elementor-widget elementor-widget-text-editor\" data-id=\"9d1e151\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h2 class=\"translation-block\"><strong>External and toxic<\/strong> causes<\/h2><p>Certain environmental factors and lifestyle habits can accelerate kidney damage:<\/p><ul><li class=\"translation-block\"><strong>Long-term use of certain medications<\/strong> : excessive or prolonged use of non-steroidal <strong>anti-inflammatory drugs (NSAIDs)<\/strong> such as ibuprofen or naproxen can <strong>impair blood flow to the kidneys<\/strong>, reducing their ability to filter blood. Other medications, including certain antibiotics and iodinated contrast agents, may also be nephrotoxic when used repeatedly.<\/li><li class=\"translation-block\"><strong>Exposure to toxic substances<\/strong> : <strong>heavy metals (such as lead, cadmium and mercury)<\/strong> and <strong>industrial solvents<\/strong> can damage the kidneys over time and contribute to the development of chronic kidney disease.<\/li><li class=\"translation-block\"><strong>Smoking and alcohol<\/strong> : although they are not direct causes of CKD, smoking and excessive alcohol consumption worsen risk factors such as <strong>high blood pressure and vascular disease<\/strong>, accelerating the progression of kidney disease.<\/li><\/ul><p><strong><br \/>Prevention and regular medical follow-up can help reduce these risks and slow the progression of chronic kidney disease.<\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-3a43a2e2 e-flex e-con-boxed e-con e-parent\" data-id=\"3a43a2e2\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-79a0988 e-con-full e-flex e-con e-child\" data-id=\"79a0988\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-81091ca elementor-align-left elementor-widget elementor-widget-button\" data-id=\"81091ca\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/nehomy.com\/en\/how-can-you-live-better-with-ckd\/\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-icon\">\n\t\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"63\" height=\"63\" viewbox=\"0 0 63 63\" fill=\"none\"><circle cx=\"31.3606\" cy=\"31.3606\" r=\"30.6479\" fill=\"white\" stroke=\"#FF6E6E\" stroke-width=\"1.42548\"><\/circle><path d=\"M21.3823 31.3607C20.5951 31.3607 19.9568 31.9989 19.9568 32.7861C19.9568 33.5734 20.5951 34.2116 21.3823 34.2116L21.3823 32.7861L21.3823 31.3607ZM47.041 32.7861L32.7862 24.5561L32.7862 41.0162L47.041 32.7861ZM21.3823 32.7861L21.3823 34.2116L34.2117 34.2116L34.2117 32.7861L34.2117 31.3606L21.3823 31.3607L21.3823 32.7861Z\" fill=\"#FF6E6E\"><\/path><\/svg>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">How can you live better with CKD?<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7dae501d elementor-widget elementor-widget-button\" data-id=\"7dae501d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/nehomy.com\/en\/what-is-ckd\/symptoms-of-ckd\/\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Back to Symptoms of CKD<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>Les causesde l&rsquo;IRC22,23 L\u2019insuffisance r\u00e9nale chronique (IRC) peut \u00eatre caus\u00e9e par plusieurs facteurs, souvent combin\u00e9s. Ces causes peuvent \u00eatre m\u00e9dicales, g\u00e9n\u00e9tiques ou li\u00e9es \u00e0 des expositions toxiques. Maladies sous-jacentes Certaines pathologies chroniques affectent directement les reins et entra\u00eenent leur d\u00e9t\u00e9rioration progressive : Le diab\u00e8te (type 1 et 2) : c\u2019est la premi\u00e8re cause d\u2019IRC dans le monde. Une glyc\u00e9mie mal contr\u00f4l\u00e9e endommage les petits vaisseaux sanguins des reins (n\u00e9phropathie diab\u00e9tique), r\u00e9duisant progressivement leur capacit\u00e9 de filtration. L\u2019hypertension art\u00e9rielle : une pression sanguine \u00e9lev\u00e9e exerce une contrainte excessive sur les vaisseaux r\u00e9naux, entra\u00eenant leur durcissement et leur r\u00e9tr\u00e9cissement, ce qui diminue leur efficacit\u00e9. Sans contr\u00f4le ad\u00e9quat, cela peut acc\u00e9l\u00e9rer la perte de la fonction r\u00e9nale. Les maladies auto-immunes : certaines maladies, comme le lupus \u00e9ryth\u00e9mateux diss\u00e9min\u00e9 ou la vascularite, attaquent les reins et provoquent une inflammation chronique des structures r\u00e9nales (glom\u00e9rules, tubules), pouvant mener \u00e0 une insuffisance r\u00e9nale progressive. La py\u00e9lon\u00e9phrite [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":6990,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":"","_members_access_role":[],"_members_access_error":""},"class_list":["post-7027","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v28.1 (Yoast SEO v28.1) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>L&#039;HDD au quotidien - Conseils Pratiques - Patients - Nehomy - H\u00e9modialyse \u00e0 Domicile<\/title>\n<meta name=\"description\" content=\"Conseils pratiques pour int\u00e9grer l\u2019h\u00e9modialyse quotidienne \u00e0 domicile\u202f: organisez vos s\u00e9ances, am\u00e9nagez un espace d\u00e9di\u00e9, suivez votre traitement et optimisez votre qualit\u00e9 de vie gr\u00e2ce \u00e0 un accompagnement adapt\u00e9.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/nehomy.com\/en\/what-is-ckd\/the-causes-of-ckd\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Quelles sont les causes ?\" \/>\n<meta property=\"og:description\" content=\"Conseils pratiques pour int\u00e9grer l\u2019h\u00e9modialyse quotidienne \u00e0 domicile\u202f: organisez vos s\u00e9ances, am\u00e9nagez un espace d\u00e9di\u00e9, suivez votre traitement et optimisez votre qualit\u00e9 de vie gr\u00e2ce \u00e0 un accompagnement adapt\u00e9.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/nehomy.com\/en\/what-is-ckd\/the-causes-of-ckd\/\" \/>\n<meta property=\"og:site_name\" content=\"Nehomy\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/Nehomy\" \/>\n<meta property=\"article:modified_time\" content=\"2026-04-27T08:43:46+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/nehomy.com\/wp-content\/uploads\/2026\/02\/image-symptome.svg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Estimated reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"4 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/nehomy.com\\\/quest-ce-que-lirc\\\/les-causes-de-lirc\\\/\",\"url\":\"https:\\\/\\\/nehomy.com\\\/quest-ce-que-lirc\\\/les-causes-de-lirc\\\/\",\"name\":\"L'HDD au quotidien - 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